Moving Beyond Isolated Systems
A whole-body approach to understanding spinal cord injury, recovery, and the current scientific evidence for neuromodulation.
Expand your knowledge about SCI treatment and recovery
March 8-10, 2021
Louisville, KY. Accessibility note: KY is the abreviation for the state of Kentucky
Moving Beyond Isolated Systems: a whole body approach to spinal cord injury, recovery, and the current scientific evidence for neuromodulation
The spinal cord is a signal integration and communication matrix that serves to maintain systemic homeostasis under varying conditions. Spinal cord injury (SCI) perturbs the ability of the spinal cord to maintain homeostasis, which has synergistic and interdependent whole-body consequences.
Neuromodulation has shown the ability to recover levels of homeostasis across many body systems. Rather than viewing the pathophysiology of SCI from an isolated organ-system perspective, this meeting will place the study of SCI in the context of medical and biological “Systems Theory” which emphasizes an integrated whole-body approach to treatment of illness and/or injury.
The goal of this meeting will be to initiate discussions and encourage dialogue that expands the focus of the SCI field from isolated organ-system dysfunction to the study of the multi-system, inter-related, consequences of spinal cord injury.
Sessions will focus on the far-reaching effects of spinal cord injury on the whole body. Session topics include Spinal Cord Injury’s Whole-Body Effect on the Autonomic System, Spinal Cord Injury and Metabolic Disease, and Muscle as an Endocrine Organ. This Symposium will offer an unprecedented focus on understanding the current science of neuromodulation and evidence to support how this practice of can improve locomotor skills, autonomic function, and overall health for persons with spinal cord injury.
March 8-10, 2021
Spinal Cord Injury as a Whole Body System: Biology and Neuromodulation as an Agent of Recovery
Steve Kirshblum, MD (8:00 am)
Plenary Session 1: Metabolic Disease (Chair: Dana McTigue, PhD)
- David Gater, MD, PhD, MS – Neuroginic obesity after SCI
- Ceren Yarar-Fisher, PhD
- Phillip Popovich, PhD
- Mark Nash, PhD, FACSM – Inhibition of Myostatin Expression as a countermeasure to sarcopenic obesityfollowing SCI
- J. Andrew Taylor, PhD –Impact of Functional Electrical Stimulation Exercise on Cardiometabolic Health in SubAcute SCI
Plenary Session 2: Muscle as endocrine organ (Chair: David Magnuson, PhD)(1:00-3:00pm)
- Christopher Cardozo, MD –Muslce as an endocrine organ: how changes in muscle secretome after SCI may drive those in fat and liver and predict adverse alterations in metabolism
- David Ditor, PhD – Targeting inflamation as a means to manage secondary health complications after SCI
- Karen Esser, M Ed, PhD – Circadian clocks in muscle; the importance of activity and exercise
Plenary Session 3: Cardiovascular Dysfunction (Chair: Jill Wecht, EdD)
- David Goldstein, MD, PhD
- Andrei Krassioukov, MD, PhD – Spinal cord Stimulation and autonomic dysfunctions following spinal cord injury
- Jill Wecht, EdD – Autonomic Cardiovascular Dysfunction in SCI: Presentation, Consequences, Treatments
- Ona Bloom, PhD –The potential for Lumbosacral Spinal Cord Epidural Stimulation to Reduce Systemic Inflammation in Chronic Spinal Cord Injury: An overview and case report
Keynote Dinner at Churchill Downs
Neuromodulation: Past, Present, & Future
Elliot Krames, MD (7:00 pm)
*Additional Ticket Required*
Overview and History of Neuromodulation
Karen Minassian, PhD (8:00 – 9:00 am)
Plenary Session 4: Epidural Stimulation: Motor Systems (Chair: Susan Harkema, PhD)
- Marco Capogrosso, PhD –Computer models in the understanding of Electrical Epidural Stimulation for the recovery of motor control
- Gregoire Courtine, PhD –Targeted epidural spinal stimulation (TESS): mechanisms
- Peter Grahn, PhD –Examining downstream electrophysiology to understand interactions between electrical stimuli and human spinal sensorimotor networks
- Enrico Rejc, PhD –Back on their feet: recovery of standing with spinal cord epidural stimulation after chronic motor complete spinal cord injury
- Claudia Angeli, PhD –From modulation to recovery: Crossing the threshold
Special Session: Neuromodulation and Motor Training:
Megan Gill, PT, DPT and Claudia Angeli, PhD –Performance focused neuromodulation
Special Discussion: How to stim? Epidural Sub-Threshold network focused? Targeted Epidural Supra-Threshold?
Gregoire Courtine, Susan Harkema, Claudia Angeli, Peter Grahn
Plenary Session 5: Transcutaneous Stimulation: Motor Systems
(Chair: Reggie Edgerton, PhD)
Yury Gerasmienko, PhD –Comprehensive approach to regain motor functions using transcutanious spinal cord stimulation
Ursula Hofstoetter, PhD –Tanscutaneous spinal cord stimulation for enhancing locomotor activity and controlling spasticity
Gail Forrest, PhD –Preliminary data for Transcutaneous Stimulation and Training for SCI: Upper and Lower extremity
Reggie Edgerton, PhD
Plenary Session 6: Neurosurgical Approaches and the Clinical Future of Neuromodulation
Maxwell Boayke, MD, MPH, MBA –Epidural stimulation for spinal cord injury-neurosurgical techniques and outcomes, pearls and pitfalls
Jocelyne Bloch, MD –Targeted epidural spinal stimulation (TESS): clinical translation
James Guest, MD, PhD, FACS –
Plenary Session 7: Intersystems, Health, and Community Integration of Neuromodulation
- Aaron Phillips, PhD –A mechanism-guided cardiovascular stabilizing system for spinal cord injury
Charles Hubscher, PhD –Epidural stimulation targeted for bladder control in a rat spinal cord injury model
April Herrity, PhD –Targeted spinal cord epidural stimulation in the recovery of bladder and cardiovascular function after human spinal cord injury
- Susan Harkema, PhD –
Plenary Session 8: Stakeholders Discussion:
Integration of Community, Industry, Science, and Funders
Kentucky International Convention Center
221 South 4th St.
Louisville, KY 40202
15 minutes from Louisville International Airport, and located at the center of downtown Louisville, the Kentucky International Convention Center (KICC) is close to more than 6,000 hotel rooms and dozens of fine dining and casual restaurants. It is within walking distance of museums, distilleries, gift shops, and other attractions. KICC is truly at the center of it all!
There are many conveniently located hotels in the area. We have blocked a limited number of rooms at The Hyatt Regency Louisville at $155 per night, and at the Louisville Marriott Downtown at $172 per night. Accessible rooms will be available and can be reserved.
Hyatt Regency Louisville
Click here to make a Hyatt reservation or call 877-803-7534 and reference”Kentucky Spinal Cord Injury Research Center.” The Hyatt Regency Louisville is also offering 20% off at the Sway Restaurant. Overnight parking is $20 self park or $29 valet.
Marriott Downtown Louisville
Click here to make a Marriott reservation. Complimentary wifi and discounted daily parking ($15/day) will be available to those staying at the Marriott for the Symposium.
The University of Louisville School of Medicine designates this live activity for a maximum of 15.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
This program has been approved by the Kentucky Board of Nursing for 18.3 continuing education credits through University of Louisville Hospital, provider number 4-0068-7-20-1148. The Kentucky Board of Nursing approval of an individual nursing education provider does not constitute endorsement of program content. Completion criteria to obtain CE’s: Attend entire session and complete the evaluation.
Occupational and Physical Therapists
This program has been approved by the Kentucky Physical Therapy Association (KPTA) for 18.5 continuing education credits for attending Physical Therapists.
This program has been approved by the Kentucky Occupational Therapy Association (KOTA) for 18.5 continuing education credits for attending Occupational Therapists.
The University of Louisville School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.